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How Long Does MDMA Comedown Last?

Depending on how much you use, an MDMA comedown can last hours or even days. The comedown for MDMA is so varied because of how the drug affects people. It stimulates the release or inhibits the uptake of feel-good chemicals in the brain like serotonin and dopamine. At the same time, it increases a user's energy levels and activity. 

Because everyone reacts differently and it is impossible to know the concentration of illicit drugs like MDMA, no comedown is the same. To help understand why we first have to learn what causes a comedown. 

MDMA Comedown Cause

The reason you feel depressed and irritable or anxious after using MDMA is that the drug radically alters your brain's chemistry. Essentially it increases the levels of dopamine and serotonin so your brain is swimming in the chemicals that make you feel happy. When the MDMA wears off your brain has used up all of its reserves of these chemicals and it takes time for it to manufacture more. This means you have to function without enough dopamine or serotonin for much longer than you’re used to. 

On top of this, the drug can cause sleep problems and dehydration which further increase the severity of a comedown. Lack of sleep can worsen irritability and anxiety while dehydration can make your feel worn down or cause other medical problems. 

If you are researching “how long does MDMA comedown last”, you are likely suffering from one right now. This can be tough and feelings of anxiety or depression only make a comedown feel longer. If you are worried about how long your comedown lasts, we can offer some advice

First, the following symptoms are common for anyone coming down from MDMA. 


  • Irritability
  • Depression
  • Aggression
  • Trouble sleeping
  • Memory issues
  • Problems concentrating
  • Anxiety
  • Lower appetite

Second, MDMA comedown can be difficult but you will get through it so do not panic. 

Third, If you are having a severe problem, you can contact your doctor or the emergency services. They are not concerned with the legality of MDMA, they just want to make sure you are ok. You can also dial the 111 NHS non-emergency number if you have questions. They can help you understand what you are going through and advise you on whether or not you should seek medical attention. 

If you feel you have a problem with MDMA, there are also resources available including Help Me Stop. We offer a variety of rehabilitation options that fit around your everyday life. Our counsellors are ready to help you understand your drug use and work with you to find alternatives to MDMA. 

You can contact us today for a free talk. Our admissions team will tell you more about our service and the treatment options we provide. If you would prefer to get treatment from home, we also offer online options.


If you have a problem with alcohol or drugs, or know someone who does, contact us for free, confidential advice:

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